Bone Loss

FDA Considers Limits on Osteoporosis Drugs Due to Fracture Risk

An advisory committee of the U.S. Food and Drug Administration (FDA) last week weighed the risks and benefits of bisphosphonate drugs such as alendronate (Fosamax) for managing osteoporosis. The committee recommended limiting the duration of bisphosphonate use, but did not agree on a time frame.alt

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Age-Related Fractures Due to Reduced Bone Quality as well as Quantity

Bone loss is a growing concern as the HIV positive population ages. Age-associated bone problems including fractures have largely been attributed to loss of bone mineral density (osteopenia and osteoporosis), but changes in the quality of bone structure play a role as well, according to recent research described in the August 22, 2011, advance edition of Proceedings of the National Academy of Sciences. alt

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IAS 2011: Coronary Artery Calcification Linked to Bone Loss

Coronary artery calcification is associated with and low femoral bone mineral density (BMD), but no such link found with lumbar spine BMD, researchers reported at IAS 2011 in Rome.


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IAS 2011: Doubt Remains if HIV Therapy Increases the Risk of Fragility Fractures

The relationship between HIV therapy and fracture risk is far from straightforward, U.S. research presented to the International AIDS Society conference in Rome suggests.

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Low CD4 Count Linked to Bone Fractures

A large Australian study found HIV positive people with lower CD4 T-cell counts were at greater risk of fractures due to bone loss. alt

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