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Pregnancy & HIV MTCT

AIDS 2016: South Africa Has Driven Mother-to-Child HIV Transmission Down to 4%

Mother-to-child transmission (MTCT) of HIV at a population level was just over 4% at 18 months of follow-up in a national evaluation in South Africa, Ameena Goga, presenting on behalf of the South African prevention of mother-to-child transmission Evaluation Group, told participants at the 21st International AIDS Conference (AIDS 2016) this week in Durban. 

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CROI 2016: Studies Probe Retention in Care for HIV+ Women Who Start ART During Pregnancy

Engaging lay counselors to provide a combination package of evidence-based interventions in Nyanza, Kenya, and addressing partner disclosure, as well as pre-treatment education about the benefits of antiretroviral therapy (ART) for maternal and child health in Malawi’s Option B+ program improved retention in care and reduced loss to follow-up of mothers with HIV and their infants, studies presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2016) show.

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CROI 2016: Option B+ Cuts Mother-to-Child HIV Transmission Dramatically in Malawi

Among women on antiretroviral therapy (ART) prior to pregnancy, early mother-to-child transmission in Malawi’s Option B+ program compares favorably to transmission rates observed in developed countries, Sundeep Gupta told participants at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) last week in Boston.

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CROI 2016: Cotrimoxazole Prophylaxis Provides No Benefit for HIV-Exposed Uninfected Children

Challenging current guidelines, prolonged use of cotrimoxazole may not be necessary for HIV-exposed but uninfected children in low-mortality, non-malarial settings with low risk for late mother-to-child transmission throug breastfeeding, Roger Shapiro told participants at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2016) in Boston.

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Oral Antiretrovirals Protect Infants from HIV Infection During Breast-Feeding

Infants born to HIV-positive mothers were less likely to become infected during their first year after birth if they received pre-exposure prophylaxis (PrEP) using liquid formulations of lamivudine or lopinavir/ritonavir while breast-feeding, according to a study from Africa published in the November 18, 2015 edition of The Lancet.

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