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IAS 2015: Indiana HIV Outbreak -- Lessons about Containing Local Outbreaks and Harm Reduction

An early 2015 outbreak of HIV and hepatitis C virus (HCV) infection in rural Indiana linked to injection of prescription opiates offers a good example to how to track and contain a localized outbreak, according to a pair of presentations at a late-breaking prevention research session at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention last month in Vancouver. Attendees at the session stressed that we already know how to prevent such outbreaks, and called for implementation of needle exchange programs and other proven-effective harm reduction measures.

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IAS 2015: Pros and Cons of PrEP -- Volunteers Recount their Experiences in ADAPT Study

The reasons people come forward for pre-exposure prophylaxis (PrEP) or take it once prescribed are likely to be very mixed, and dependent as much on local political and cultural beliefs as they are on more personal factors like relationship status, researchers reported at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) last month in Vancouver.

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IAS 2015: Cash to Stay in School Didn't Reduce HIV Incidence, but Attendance Protects Young Women

A conditional cash transfer to the households of adolescent girls to promote school attendance did not reduce HIV incidence in a randomized study in rural South Africa, Audrey Pettifor of the University of North Carolina reported at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last month in Vancouver. Although receipt of the cash transfer was not associated with reduced HIV incidence, it was associated with a lower rate of unprotected sexual intercourse compared to a control group.

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IAS 2015: People with Hepatitis B Can Safely Use Truvada PrEP for HIV Prevention

People with hepatitis B virus (HBV) infection did not experience liver inflammation "flares" or other adverse events when they used or stopped using Truvada for HIV pre-exposure prophylaxis (PrEP), according to an analysis from the iPrEx study presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention last month in Vancouver. This is a potential concern because the drugs in Truvada -- tenofovir and emtricitabine -- are active against HBV as well as HIV.

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IAS 2015: Cash Encourages Circumcision, Prevention of Mother-to-Child HIV Transmission

Cash compensation can improve the uptake of key HIV prevention services in sub-Saharan Africa, according to results from 2 randomized studies presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last month in Vancouver. A randomized trial conducted in Nyanza province, Kenya, showed that offering compensation in the form of food vouchers resulted in a significantly higher uptake of medical male circumcision, while a second randomized trial conducted in the Democratic Republic of Congo showed that providing modest cash incentives significantly increased retention in services for prevention of mother-to-child HIV transmission.

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